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This study suggests that testosterone administration has long-term effects on skeletal muscle that scientists still know very little about,” said Dr. Mark Hyman, president of the Endocrine Society and medical director of the Center for Molecular and Cell Physiology at the University of Pennsylvania. “But, even though our findings are preliminary, this report points to the importance of using testosterone as a treatment for androgen deficiency in men.” Dr. Hyman is co-author of the review paper, which appears in the January 17 online edition of Endocrine.
A previous examination found that post-menopausal men treated with testosterone for two years had higher levels of testosterone in skeletal muscle than their age-matched controls, the researchers said. As women and men age, testosterone levels increase.
The current study also examined the effects of testosterone during a 14-month period of the treatment on muscle mass, strength and function. Muscle mass measures the weight of a person’s musculature, and strength measures strength and physical function, including ability to climb a staircase and lift weights. Fat mass is a measure of one’s body fat percentage.
Women undergoing the study had average or higher post-menopausal testosterone levels than men who had not received this treatment, which may reflect a greater effect of the therapy on men, the researchers said.
Follow Rachael Rettner @RachaelRettner. Follow Live Science @livescience, Facebook & Google+. Originally published on Live Science.
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